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瀏覽次數(shù)：149Maybridge小分子雜環(huán)中間體、醫(yī)藥化學(xué)服務(wù)和篩選化合物庫
Maybridge成立于1962年，是Thermo Fisher Scientific Inc集團(tuán)下專為藥物研發(fā)和生物技術(shù)提供相關(guān)產(chǎn)品和服務(wù)的特殊供應(yīng)商，Maybridge公司47年來一直致力于為客戶設(shè)計(jì)和提供創(chuàng)新性雜環(huán)中間體，以幫助客戶發(fā)現(xiàn)和設(shè)計(jì)新的有價(jià)值的藥物分子，助力藥物發(fā)現(xiàn)工作。
Maybridge產(chǎn)品包括具有多變化系列的小分子雜環(huán)中間體、醫(yī)藥化學(xué)服務(wù)和篩選化合物庫。并能在客戶需要時(shí)進(jìn)行適當(dāng)放大生產(chǎn)。
Maybridge篩選化合物庫
篩選化合物庫提供超過56000種不同的藥類分子，并且篩選出靶標(biāo)化合物的幾率很高， 大部分都是創(chuàng)新化合物，業(yè)界內(nèi)*具有多樣性的化合物庫，符合“Lipinski五規(guī)則"，具有較好的性能，含有強(qiáng)效團(tuán)以保證與生物靶點(diǎn)作用。Maybrdige篩選化合物庫在新藥研發(fā)領(lǐng)域起到關(guān)鍵作用，例如新藥Sorafenib，Olaparib和Sunitinib的開發(fā)
2）Maybridge HitFinderTM化合物庫
篩選化合物庫的子集HitFinderTM加速了先導(dǎo)化合物的鑒定，提供14400種優(yōu)質(zhì)篩選化合物并提供現(xiàn)貨供應(yīng)，從每個(gè)相似化合物簇中選擇一個(gè)化合物組成HitFinderTM化合物庫，化合物以干膜狀態(tài)儲存在96或384孔板中，方便客戶使用和儲存，可提供放大生產(chǎn)以滿足先導(dǎo)化合物優(yōu)化的需要。
Maybridge片段庫
片段庫提供超過30000種片段分子和領(lǐng)xian的預(yù)選化合物庫，加速基于結(jié)構(gòu)的先導(dǎo)化合物的鑒定
1）Maybridge Ro3片段庫
提供1000種藥類分子，含有強(qiáng)藥效團(tuán)和具有you越的ADME性質(zhì)結(jié)構(gòu)， 結(jié)構(gòu)多樣性廣，含有容易結(jié)合的集團(tuán)，靶標(biāo)化合物可快速轉(zhuǎn)變成較大的先導(dǎo)化合物，wan全符合“Rule of Three"，具有較好的性能，保證溶解性（DMSO）。 直接使用：客戶定量稱量，化合物儲存在玻璃瓶或多孔板中，并可提供放大生產(chǎn)你滿足先導(dǎo)化合物優(yōu)化的需要。
2）其他的特殊片段庫包括
Maybridge溴-片段庫
提供超過1500中含溴片段的化合物，用于基于X-射線的片段篩選
Maybridge氟-片段庫
提供超過5300種含氟片段化合物，用于于19F NMR的片段篩選
Maybridge前體-片段庫
提供有價(jià)值的活性“前體片段庫"用于合成片段庫或開發(fā)靶標(biāo)化合物
Maybridge品牌部分產(chǎn)品訂購信息：
Casno | 貨號 | 規(guī)格 | 品名 | |
2144-37-8 | BLT00257EA | 10GR | Methyl 5-(chloromethyl)-2-furoate, 95% 甲基 5-(氯甲基)-2-糠酸酯 | |
2144-37-8 | BLT00257EB | 25GR | Methyl 5-(chloromethyl)-2-furoate, 95% 甲基 5-(氯甲基)-2-糠酸酯 | |
21815-91-8 | BTB00300DA | 1GR | 3-Chlorobenzo[b]thiophene-2-carbonyl chloride, 97% 3-氯苯并[b]噻酚-2-羰酰氯 | |
21815-91-8 | BTB00300EA | 10GR | 3-Chlorobenzo[b]thiophene-2-carbonyl chloride, 97% 3-氯苯并[b]噻酚-2-羰酰氯 | |
97051-69-9 | BTB00739DA | 1GR | N1-[2-Amino-4-(trifluoromethyl)phenyl]acetamide, 97% N1-[2-氨基-4-(三氟甲基)苯基]乙酰胺 | |
13134-76-4 | BTB04875EA | 10GR | Methyl 3-hydroxybenzo[b]thiophene-2-carboxylate, 97% 甲基 3-羥基苯并[b]噻吩-2-羧酸酯 | |
5819-40-9 | BTB05698EA | 10GR | 4-Bromo-5-methylisoxazol-3-amine, 97% 3-氨基-4-溴-5-甲基異 | |
1889-78-7 | DP00542CB | 250MG | 2-Bromo-1-(4-chlorophenyl)-2-phenylethan-1-one, 95% 2-溴-1--2-苯基乙烷-1-酮 | |
57260-71-6 | AW01051ZZ | GR | tert-Butyl tetrahydropyrazine-1(2H)-carboxylate, 97% 1-Boc- | |
175135-00-9 | BTB02778ZZ | GR | 4-(2-Chloro-6-nitrophenoxy)benzene-1-sulfonyl chloride, 97% | |
68337-15-5 | AC18635ZZ | GR | 4-(1H-1,2,4-Triazol-1-yl)phenol, 97% 4-(1,2,4-三唑基）苯酚 | |
AC19919ZZ | GR | 3-piperidinecarboxylic acid, 97% 六氫yan堿酸 | ||
21815-91-8 | BTB00300ZZ | GR | 3-Chlorobenzo[b]thiophene-2-carbonyl chloride, 97% 3-氯苯并[b]噻酚-2-羰酰氯 | |
132915-80-1 | BTB05127ZZ | GR | 3-Chloro-5-(trifluoromethyl)benzene-1,2-diamine, 97% 3-氯-4,5-二氨基三氟甲ben | |
701-43-9 | BTB03706ZZ | GR | 3-Chloro-4-fluorobenzamide, 97% 3-氯-4-氟ben甲酰胺 | |
113170-72-2 | BTB05134ZZ | GR | 3-Bromo-5-(trifluoromethyl)benzene-1,2-diamine, 97% 3-溴-5-三氟甲基-1,2-ben二胺 | |
2973-76-4 | BTB06293ZZ | GR | 3-Bromo-4-hydroxy-5-methoxybenzaldehyde, 97% 5-溴香蘭素 | |
16789-84-7 | BTB03755ZZ | GR | 3-Bromo-2-hydroxy-5-nitrobenzaldehyde, 97% | |
3949-36-8 | BTB03234ZZ | GR | 3-Acetyl-2H-chromen-2-one, 97% 3-乙酰基香豆su | |
175135-15-6 | BTB05684ZZ | GR | 3-[5-(Trifluoromethyl)-1H-benzo[d]imidazol-2-yl]propan-1-ol, 97% | |
97051-69-9 | BTB00739ZZ | GR | N1-[2-Amino-4-(trifluoromethyl)phenyl]acetamide, 97% | |
5434-30-0 | BTB00549ZZ | GR | N1-(5-Amino-2-methylphenyl)acetamide, 97% | |
2144-37-8 | BLT00257ZZ | GR | Methyl 5-(chloromethyl)-2-furoate, 95% | |
13134-76-4 | BTB04875ZZ | GR | Methyl 3-hydroxybenzo[b]thiophene-2-carboxylate, 97% | |
14742-32-6 | AW01254ZZ | GR | 2-Amino-5-phenyl-3-furonitrile, 95% | |
609-85-8 | BTB01924ZZ | GR | 2-Amino-3,5-dibromobenzoic acid, 95% 2-氨基-3,5-二溴苯甲酸 | |
175135-09-8 | BTB04528ZZ | GR | 2,6-Dibromo-3-chloro-4-fluoroaniline, 97% 3-氯-2,6-二溴-4-氟ben胺 | |
21663-61-6 | DP01309ZZ | GR | 2,5-Dichlorobenzonitrile, 97% 2,5-二氯苯腈 | |
71083-06-2 | BTB02003ZZ | GR | Ethyl 8-fluoro-4-hydroxy-3-quinolinecarboxylate, 97% | |
62482-30-8 | BTB00099ZZ | GR | Ethyl 6-bromo-2-methylquinoline-4-carboxylate, 95% | |
30806-83-8 | AC17031ZZ | GR | Ethyl 4-isocyanatobenzoate, 97% 乙基-4-異疊酸苯酯 | |
23795-02-0 | BTB00914ZZ | GR | Ethyl 3-(4-hydroxyphenyl)propanoate, 97% | |
4815-37-6 | AW00937ZZ | GR | Ethyl 2-amino-5-methyl-4-phenylthiophene-3-carboxylate, 97% | |
6193-47-1 | AC11174ZZ | GR | Cyclopropyl(2-thienyl)methanone, 97% 環(huán)丙基-2-噻吩基甲酮 | |
175135-07-6 | BTB04184ZZ | GR | Benzo[b]thiophene-2-carbohydrazide, 97% 苯并[b]噻吩-2-羧酰肼 | |
145-74-4 | BTB06262ZZ | GR | 8-Chloronaphthalene-1-sulfonic acid, 97% | |
175135-22-5 | BTB06368ZZ | GR | 2-(Propylthio)nicotinic acid, 97% | |
175135-23-6 | BTB06369ZZ | GR | 2-(Pentylthio)nicotinic acid, 97% | |
74470-23-8 | BTB06287ZZ | GR | 2-(Methylthio)nicotinic acid, 97% 2-(甲硫基)煙酸 | |
40241-78-9 | DP01481ZZ | GR | 2-(Methylthio)-4,5-dihydro-1H-imidazole hydrobromide, 95% | |
175135-27-0 | BTB06390ZZ | GR | 2-(Ethylthio)nicotinamide, 97% | |
76254-70-1 | DP01591ZZ | GR | 2-(4-Nitrophenyl)ethanethioamide, 97% | |
33599-26-7 | BTB03301ZZ | GR | 2-(4-Chlorophenyl)-2-morpholinoacetonitrile, 97% | |
5157-08-4 | BTB06143ZZ | GR | 6-Methyl-2,3,4,5-tetrahydropyridazin-3-one, 97% 4,5-二氫-6-甲基噠嗪-3(2H)-酮 | |
5469-69-2 | BTB05877ZZ | GR | 6-Chloropyridazin-3-amine, 97% 3-氨基-6-氯代噠嗪 | |
95-24-9 | BTB04800ZZ | GR | 6-Chloro-1,3-benzothiazol-2-amine, 97% 2-氨基-6-氯苯并噻唑(99%) | |
4721-98-6 | BTB04055ZZ | GR | 6,7-Dimethoxy-1-methyl-3,4-dihydroisoquinoline, 97% | |
218457-66-0 | BTB03829ZZ | GR | 6-(4-Chloro-3,5-dimethylphenoxy)pyridin-3-amine, 90% | |
698-63-5 | AC17386ZZ | GR | 5-Nitro-2-furaldehyde, 97% 5-硝基糠醛 | |
6537-46-8 | BTB03140ZZ | GR | 5H-Chromeno[2,3-b]pyridin-5-one, 97% 1-氮雜 | |
436-72-6 | BTB04061ZZ | GR | 5-Fluoroquinazolin-4-ol, 97% | |
23602-63-3 | BTB03914ZZ | GR | 5-Chloro-2-hydroxy-3-methylbenzaldehyde, 95% 5-氯-2-羥基-3-ji甲基ben甲醛 | |
5034-74-2 | BTB03758ZZ | GR | 5-Bromo-2-hydroxy-3-methoxybenzaldehyde, 97% | |
465514-39-0 | AW01250ZZ | GR | 1-[4-(Trifluoromethyl)-2-pyrimidinyl]-4-piperidinecarboxylic acid, 97% | |
58315-38-1 | BTB03244ZZ | GR | 1-[2-Nitro-4-(trifluoromethyl)phenyl]piperazine, 97% | |
219539-29-4 | BTB05406ZZ | GR | 1-[2-(4-Chlorophenyl)-6H-1,3-thiazin-5-yl]ethan-1-one, 97% | |
20555-91-3 | BTB06155ZZ | GR | 1,2-Dichloro-4-iodobenzene, 97% 3,4-二氯碘苯 | |
394-32-1 | BTB04130ZZ | GR | 1-(5-Fluoro-2-hydroxyphenyl)ethan-1-one, 97% 5-氟-2-羥基苯乙酮 | |
19462-98-7 | BTB02521ZZ | GR | 5,6-Dichloro-1H-benzo[d]imidazole-2-thiol, 95% 5,6-二氯苯咪唑-2-硫 | |
852180-39-3 | AW01246ZZ | GR | 5-(3-Pyridinyloxy)-2-furoic acid, 97% | |
2359-60-6 | BTB05830ZZ | GR | 4-Piperidinoaniline, 97% 4-(1-哌啶基)苯胺 | |
38869-37-3 | AC10033ZZ | GR | 4-Piperazinophenol dihydrobromide, 97% | |
3967-01-9 | BTB00610ZZ | GR | 4-Methyl-1,3,4,5-tetrahydro-2H-1,5-benzodiazepin-2-one, 97% | |
306934-78-1 | AW01194ZZ | GR | 4-Chloro-5-methyl-6-phenylthieno[2,3-d]pyrimidine, 97% | |
140675-42-9 | BTB04131ZZ | GR | 1-(3,5-Difluoro-2-hydroxyphenyl)ethan-1-one, 97% | |
175135-14-5 | BTB05258ZZ | GR | 4-Bromo-6-(trifluoromethyl)-1H-benzo[d]imidazole, 97% | |
5819-40-9 | BTB05698ZZ | GR | 4-Bromo-5-methylisoxazol-3-amine, 97% 3-氨基-4-溴-5-甲基異 | |
62054-72-2 | BTB01843ZZ | GR | 4-[2-Nitro-4-(trifluoromethyl)phenyl]morpholine, 97% | |
306934-75-8 | AW01128ZZ | GR | 4-[(2-Chloro-6-fluorobenzyl)oxy]-3-methoxybenzaldehyde, 97% | |
932-22-9 | BTB06282ZZ | GR | 4,5-Dichloro-3-pyridazinol, 95% 4,5-二氯噠嗪-3(2H)-酮 | |
440-60-8 | AC18836ZZ | GR | (2,3,4,5,6-Pentafluorophenyl)methanol, 97% 五氟芐醇 | |
175135-06-5 | BTB03983ZZ | GR | 3,5-Dichloro-4-(2-chloro-4-nitrophenoxy)benzene-1-sulfonyl chloride, 97% | |
90-59-5 | BTB02697ZZ | GR | 3,5-Dibromo-2-hydroxybenzaldehyde, 95% 3,5-二溴水yang醛 | |
725-89-3 | DP01857ZZ | GR | 3,5-Di(trifluoromethyl)benzoic acid, 97% 3,5-雙(三氟甲基)苯甲酸 | |
3430-40-8 | BTB03853ZZ | GR | 2-Piperidinobenzamide, 97% | |
39643-31-7 | BTB02217ZZ | GR | 2-Piperidinoaniline, 97% 2-(1-哌啶基)ben胺 | |
5585-33-1 | BTB02219ZZ | GR | 2-Morpholinoaniline, 97% 4-2-胺苯基嗎啉 | |
613-30-9 | BTB06234ZZ | GR | 2-Methyl-6-nitroquinoline, 97% 2-甲基-6-硝基喹lin | |
113170-71-1 | BTB04900ZZ | GR | 2-Bromo-6-nitro-4-(trifluoromethyl)aniline, 97% | |
1889-78-7 | DP00542ZZ | GR | 2-Bromo-1-(4-chlorophenyl)-2-phenylethan-1-one, 95% | |
205178-80-9 | BTB02944ZZ | GR | 2-Bromo-1-(4-chloro-3-methylphenyl)ethan-1-one, 97% | |
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